Hydrochloric Acid → HCID 46856191, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of 1-(1,1-dimethylethyl) 3-methyl 4-(4-chlorophenyl)-5,6-dihydro-1,3(2H)-pyridinedicarboxylate (P29, 1.85 g) in diethylether (37.04 mL) at −20° C., LiAlH4 1M solution in diethylether (3.68 mL) was added dropwise and the resulting mixture was stirred at −20° C. for 20 min. A solution of HCl 2% in water (4.44 mL), diethylether and water were added and the organic phase was separated, dried over Na2SO4, filtered and evaporated under reduced pressure to obtain the title compound (1.487 g).

Provenance & Evidence