Hydrochloric Acid → HCID 68547925, compound

Participants

Reaction Steps

(1S,6R)-6-(3,4-dichlorophenyl)-3-methyl-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane (E12, 16 mg) was treated with hydrochloric acid 1.0M in diethyl ether (0.064 mL). 0.5 mL of diethyl ether were added and a colourless solid formed. Organic phase was removed after decantation of the solid. Colourless solid obtained as a 5:1 mixture of isomers due protonation on the nitrogen atom (16 mg).

Provenance & Evidence