HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 75234083, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 56657240 | HCID 56657240 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 75234083 | HCID 75234083 | 144.3% |
Reaction Steps
To a solution of (1R,6S or 1S,6R)-6-(3,4-dichlorophenyl)-1-[(ethyloxy)methyl]-3-azabicyclo[4.1.0]heptane (E19a, 11 mg) in DCM (0.2 ml) was added 1 equivalent of HCl (1M in Et2O), the solvent evaporated under vacuo and the material thus obtained triturated with Et2O to give 8.9 mg of the title compound as a white slightly hygroscopic solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691893B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-0339bd0adfee4a0e8347fccf2b335df9 |
| Source note | uspto-grants-2010_04 |