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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639860Generated: October 31, 2026

Hydrochloric Acid → HCID 75234083, compound

https://huagongshe.com/reaction/639860

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 56657240HCID 56657240—
SolventDichloromethaneHCID 6344—
ProductHCID 75234083HCID 75234083144.3%

Reaction Steps

To a solution of (1R,6S or 1S,6R)-6-(3,4-dichlorophenyl)-1-[(ethyloxy)methyl]-3-azabicyclo[4.1.0]heptane (E19a, 11 mg) in DCM (0.2 ml) was added 1 equivalent of HCl (1M in Et2O), the solvent evaporated under vacuo and the material thus obtained triturated with Et2O to give 8.9 mg of the title compound as a white slightly hygroscopic solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691893B2
Source datasetuspto-grants-2010_04
ORD IDord-0339bd0adfee4a0e8347fccf2b335df9
Source noteuspto-grants-2010_04