HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → HCID 11818604, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 1-Chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile | HCID 11426414 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 11818604 | HCID 11818604 | — |
Reaction Steps
To a solution of 1-chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile (50 mg) in 1 mL of DMF was added NaOMe (3 equivalents). The reaction was stirred at room temp overnight, then concentrated and purified by flash chromatography (30% EtOAc/hexanes). Trituration (ether/hexanes) of the concentrated material gave the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691879B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-61f9f8455ebc449b9e3d5a777a59db91 |
| Source note | uspto-grants-2010_04 |