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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639908Generated: October 29, 2026

2-Pyridinemethanamine → 6-Methoxy-4-phenyl-1-[(pyridin-2-ylmethyl)amino]isoquinoline-3-carbonitrile

https://huagongshe.com/reaction/639908

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinemethanamineHCID 19509—
Reactant(Allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11358963—
Product6-Methoxy-4-phenyl-1-[(pyridin-2-ylmethyl)amino]isoquinoline-3-carbonitrileHCID 11233918—

Reaction Steps

Following the procedure for 1-(allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using (pyridin-2-ylmethyl)amine in place of allylamine and heating for 35 min instead of 1 h, the title compound was synthesized.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691879B2
Source datasetuspto-grants-2010_04
ORD IDord-f6e263d54b774ec0928c33326666eb8b
Source noteuspto-grants-2010_04