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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639912Generated: October 30, 2026

4-(3-Fluorophenyl)-6-methoxyisoquinoline-3-carbonitrile → 4-(2-Fluorophenyl)-6-methoxyisoquinoline-3-carbonitrile

https://huagongshe.com/reaction/639912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Fluorophenyl)-6-methoxyisoquinoline-3-carbonitrileHCID 11150121—
Reactant1-Chloro-4-(3-fluorophenyl)-6-methoxyisoquinoline-3-carbonitrileHCID 11243897—
Reactant1-Chloro-4-(2-fluorophenyl)-6-methoxyisoquinoline-3-carbonitrileHCID 11335963—
Product4-(2-Fluorophenyl)-6-methoxyisoquinoline-3-carbonitrileHCID 11737513—

Reaction Steps

Following the procedure for 4-(3-fluorophenyl)-6-methoxyisoquinoline-3-carbonitrile, using 1-chloro-4-(2-fluorophenyl)-6-methoxyisoquinoline-3-carbonitrile in place 1-chloro-4-(3-fluorophenyl)-6-methoxyisoquinoline-3-carbonitrile, the title compound was synthesized.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691879B2
Source datasetuspto-grants-2010_04
ORD IDord-7219114d5e034d71b092d487bf597459
Source noteuspto-grants-2010_04