HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-(4-nitro-1H-pyrazol-1-yl)acetate → tert-butyl 2-(4-amino-1H-pyrazol-1-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-(4-nitro-1H-pyrazol-1-yl)acetate | HCID 50999842 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | tert-butyl 2-(4-amino-1H-pyrazol-1-yl)acetate | HCID 61285781 | 99% |
Reaction Steps
Tert-butyl (4-nitro-1H-pyrazol-1-yl)acetate (1.0 g, 4.40 mmol) and 10% palladium on carbon (0.100 g) in methanol (20 ml) were stirred under an atmosphere of hydrogen for 2 hours and then the mixture was filtered through Celite and the filtrate evaporated to give tert-butyl (4-amino-1H-pyrazol-1-yl)acetate
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691867B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-5975857cff094ac4882ab5a9ca9e10f4 |
| Source note | uspto-grants-2010_04 |