反应详情

A solution of ethyl 2-morpholinoacetate (1.8 g, 11.44 mmol) in 8 N HCl (5 ml) was heated at 90° C. for 12 h. The mixture was concentrated to give the product in 64% yield (0.9 g). LC-MS (ESI): Calculated mass: 145.16; Observed mass: 146.3 [M+H]+ (rt: 0.21 min).

1. concentrationThe mixture was concentrated
2. customto give the product in 64% yield (0.9 g)
3. custom146.3 [M+H]+ (rt: 0.21 min)