HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Butene, 1-bromo-3-methyl- → 3-Methyl-7-(3-methyl-2-buten-1-yl)-8-bromo-xanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Butene, 1-bromo-3-methyl- | HCID 70092 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione | HCID 1548797 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Methyl-7-(3-methyl-2-buten-1-yl)-8-bromo-xanthine | HCID 3435331 | — |
Reaction Steps
15.37 ml of Hünig base and 9.98 ml of 3,3-dimethylallylbromide are added to 20.00 g of 3-methyl-8-bromo-xanthine in 200 ml of N,N-dimethylformamide. The reaction mixture is stirred for about half an hour at ambient temperature and then diluted with 500 ml of water. The precipitate formed is suction filtered, washed with water and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696212B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-cac098f67e724de69b623b11972842d7 |
| Source note | uspto-grants-2010_04 |