HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 117777724, compound → HCID 117777754, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 117777724 | HCID 117777724 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 117777754 | HCID 117777754 | 27% |
Reaction Steps
A solution of the compound of Example 164 (0.48 g, 0.91 mmol) in 6 N HCl (10 ml) was heated at 70° C. for 3 h. The mixture was quenched with NaHCO3 solution and extracted as in Example 1(d). The solvent was distilled off to afford the product in 27% yield (0.12 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447091B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-ccefbc40f59147c09cbe309fc031aee3 |
| Source note | uspto-grants-2016_09 |