反应详情

温度

100 °C

To a solution of the compound of Example 152 (2.1 g, 4.895 mmol) in ethanol (50 ml) was added 10% aqueous solution of NaOH (10 ml) and the mixture was heated at 100° C. for 2 h. The mixture was quenched and extracted as in Example 1(d). The solvent was distilled off to afford the product in 89% yield (1.6 g).

1. customThe mixture was quenched
2. extractionextracted as in Example 1(d)
3. distillationThe solvent was distilled off
4. customto afford the product in 89% yield (1.6 g)