反应详情

Example 43 was synthesized following a similar procedure described in the synthesis of Example 5 by reaction of compound 2A and piperazine. 1H NMR (400 MHz, CDCl3) δ 7.61 (d, J=8.0 Hz, 1 H) 7.56 (d, J=8.0 Hz, 1 H) 6.99 (t, J=8.0 Hz, 1 H) 3.93 (m, 1 H) 3.77 (m, 1 H) 3.51 (s, 3 H) 3.25 (s, 3 H) 3.17 (m, 4 H) 2.98 (m, 1 H) 2.52 (m, 1 H). [M+H] calc'd for C17H19FIN5O3, 488; found, 488.

1. customExample 43 was synthesized