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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 641787Generated: October 30, 2026

Formic Acid → HCID 178522008, compound

https://huagongshe.com/reaction/641787

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormic AcidHCID 284—
ReactantHCID 178522007HCID 178522007—
ProductHCID 178522008HCID 178522008—

Reaction Steps

2.4 A solution of 50 mg of “A2” in 1 ml of formic acid (98-100%) is refluxed for 8 hours and subsequently purified via an RP18 column, giving 3 mg of 1-[4-(4-hydroxy-3H-imidazo[4,5-c]pyridin-2-ylmethyl)phenyl]-3-(2-fluoro-5-trifluoromethylphenyl)urea (“A3”), Rf 2.88.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696224B2
Source datasetuspto-grants-2010_04
ORD IDord-4c3f601eac454f488368093faf222299
Source noteuspto-grants-2010_04