Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642181Generated: October 27, 2026

2-Fluoro-4-hydroxybenzoic Acid → (2-Fluoro-4-hydroxy-phenyl)-[2-(S)(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone

https://huagongshe.com/reaction/642181

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-hydroxybenzoic AcidHCID 2783398—
Reactant(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidineHCID 46911921—
Product(2-Fluoro-4-hydroxy-phenyl)-[2-(S)(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanoneHCID 11960537—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure A from 2-fluoro-4-hydroxybenzoic acid and 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) 307.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696234B2
Source datasetuspto-grants-2010_04
ORD IDord-54472061dfa64c7fbbd80c315d20d2da
Source noteuspto-grants-2010_04