HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 1-(3,4-Dichlorophenyl)-4-(3-iodopropyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Iodine | HCID 807 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 3-(4-(3,4-Dichlorophenyl)piperazine-1-yl)propan-1-ol | HCID 13097930 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(3,4-Dichlorophenyl)-4-(3-iodopropyl)piperazine | HCID 68006994 | — |
Reaction Steps
Compound 7p was mixed with triphenylphosphine resin, imidazole and iodine in DCM as described in General Procedure B. The product compound 11p was used without further purification for the next reaction. MS (LC/MS, ESI): 399 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447122B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-19cbbae58e7f411182f1a9ece29fe70c |
| Source note | uspto-grants-2016_09 |