Hydrochloric Acid → HCID 68577659, compound

Participants

Reaction Steps

To a solution of [4-(Pyridin-2-ylmethoxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone (1.94 g, 5.3 mmol) in diethyl ether and methanol is added a solution of HCl in ether (10.7 mmol, 1M). The mixture is concentrated, and the oily residue is dissolved in a mixture of diethyl ether and methanol and again concentrated. The solid is triturated with petroleum ether, and the solid is dried to yield 2.2 g of a yellowish solid MS (ES+) 1366.3

Provenance & Evidence