HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine → [2,6-Difluoro-4(pyridin-2-ylmethoxy)-phenyl]-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine | HCID 46911921 | — |
| Reactant | 2,6-Difluoro-4-(pyridin-2-ylmethoxy)-benzoic Acid Methyl Ester | HCID 57685124 | — |
| Product | [2,6-Difluoro-4(pyridin-2-ylmethoxy)-phenyl]-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone | HCID 11575240 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure F from 2,6-Difluoro-4-(pyridin-2-ylmethoxy)-benzoic acid methyl ester and 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) 416.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696234B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-2bb1813f0592406e93861004505b74c6 |
| Source note | uspto-grants-2010_04 |