HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine → [2-Fluoro-4-(4-methanesulfonyl-benzyloxy)-phenyl]-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine | HCID 46911921 | — |
| Reactant | 2-Fluoro-4-(4-methanesulfonyl-benzyloxy)-benzoic Acid Methyl Ester | HCID 57685125 | — |
| Product | [2-Fluoro-4-(4-methanesulfonyl-benzyloxy)-phenyl]-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone | HCID 11612583 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure F from 2-fluoro-4-(4-methanesulfonyl-benzyloxy)-benzoic acid methyl ester and 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) 475.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696234B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-77f28e25ed194d7c9386166b1d8a0c91 |
| Source note | uspto-grants-2010_04 |