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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642222Generated: October 30, 2026

Ethyl 2-((tert-butoxycarbonyl)amino)acetate → 1-Benzyl-4,5-dibromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1H-pyrrole-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642222

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-((tert-butoxycarbonyl)amino)acetateHCID 357729—
Reactant1-Benzyl-4,5-dibromo-2-bromomethyl-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68426368—
Product1-Benzyl-4,5-dibromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68426057—

Reaction Steps

Prepared in analogy to that of Example 1(c) from 1-benzyl-4,5-dibromo-2-bromomethyl-1H-pyrrole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 623 (M+Na+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-1dbac41543814bc4bac7787f020cb66e
Source noteuspto-grants-2010_04