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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642248Generated: October 30, 2026

Ethyl 2-((tert-butoxycarbonyl)amino)acetate → 4,5-Dibromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642248

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-((tert-butoxycarbonyl)amino)acetateHCID 357729—
Reactant4,5-Dibromo-2-bromomethyl-1-methyl-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68426546—
Product4,5-Dibromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1-methyl-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68428206—

Reaction Steps

Prepared in analogy to that of Example 1(c) from 4,5-dibromo-2-bromomethyl-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 549 (M+Na+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-d68ee103155f423bbfb1b9928b571d71
Source noteuspto-grants-2010_04