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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642249Generated: October 29, 2026

2-(4-Fluoro-phenyl)-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester → 2,3-Dibromo-4-hydroxy-1-methyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluoro-phenyl)-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68427850—
Reactant4,5-Dibromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1-methyl-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68428206—
Product2,3-Dibromo-4-hydroxy-1-methyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68426535—

Reaction Steps

Prepared in analogy to that of 2-(4-fluoro-phenyl)-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester from 4,5-Dibromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester. The title compound, ESI MS (m/z): 377 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-b65387aa43e642c885414a9c66b1bfef
Source noteuspto-grants-2010_04