HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester → 2-Bromomethyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester | HCID 15953410 | — |
| Reactant | 4-bromo-2-bromomethyl-5-(4-fluoro-phenyl)-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 68427627 | — |
| Product | 2-Bromomethyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester | HCID 68427498 | — |
Reaction Steps
Prepared in analogy to that of 4-bromo-2-bromomethyl-5-(4-fluoro-phenyl)-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester from 2-Methyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester. The title compound, 1H NMR (200 MHz, CDCl3): δ (ppm)=8.21 (d, 1H), 7.6-6.9 (m, 8H), 4.89 (s, 2H), 4.47 (q, 2H, J=7.4 Hz), 1.50 (q, 3H, J=7.4 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696223B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-3987ee306c274b7084159b5bcc365854 |
| Source note | uspto-grants-2010_04 |