Ammonium formate → HCID 68426685, compound

HRID 642418Notes

Reaction equation

HRID 642418 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[N:10]([CH3:22])[C:11]3[C:16]([C:17]=2[C:18]=1[OH:19])=[CH:15][C:14](Br)=[CH:13][C:12]=3Br)=[O:5])[CH3:2].C([O-])=O.[NH4+]>[Pd]>[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[N:10]([CH3:22])[C:11]3[C:16]([C:17]=2[C:18]=1[OH:19])=[CH:15][CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 2723923Ammonium formateHCID 68428469HCID 68428469, compound

Product 1

HCID 68426685HCID 68426685, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Prepared in analogy to that of Example 6(a) from 6,8-dibromo-4-hydroxy-9-methyl-9H-beta-carboline-3-carboxylic acid ethyl ester, ammonium formate and Pd/C. The title compound: 1H NMR (200 MHz, CDCl3): δ (ppm)=11.71 (s, 1H), 8.51 (s, 1H), 8.41 (d, 1H, J=7.8 Hz), 7.64-7.24 (m, 3H), 4.56 (q, 2H, J=7.1 Hz), 3.97 (s, 3H), 1.52 (t, 3H, J=7.1 Hz).

Sources & evidence

ORD record
ord-4638f52883dc45c08bd19935d19f9dcf
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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