Chlorosuccinimide → HCID 68427544, compound

HRID 642501Notes

Reaction equation

HRID 642501 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([O:24][C:25](=[O:27])[CH3:26])=[C:8]2[CH:16]=[CH:15][N:14]([C:17]3[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=3)[C:9]2=[C:10]([C:12]#[N:13])[N:11]=1)=[O:5])[CH3:2].C1C(=O)N([Cl:35])C(=O)C1>CC#N>[CH2:1]([O:3][C:4]([C:6]1[C:7]([O:24][C:25](=[O:27])[CH3:26])=[C:8]2[C:16]([Cl:35])=[CH:15][N:14]([C:17]3[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=3)[C:9]2=[C:10]([C:12]#[N:13])[N:11]=1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 68426534HCID 68426534, compound

Product 1

HCID 68427544HCID 68427544, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared in analogy to that of Example 124(b) from 4-acetoxy-7-cyano-1-(4-fluoro-phenyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester and NCS in MeCN. The title compound, ESI MS (m/z): 402 (M+H)+.

Sources & evidence

ORD record
ord-f688a2f6f94548908a5e9497f84a9e1e
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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