Ammonium formate → HCID 68427603, compound

HRID 642513Notes

Reaction equation

HRID 642513 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:26])=[C:8]2[C:14](Br)=[C:13](Br)[N:12]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([O:24][CH3:25])[CH:19]=3)[C:9]2=[CH:10][N:11]=1)=[O:5])[CH3:2].C([O-])=O.[NH4+]>[Pd]>[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:26])=[C:8]2[CH:14]=[CH:13][N:12]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([O:24][CH3:25])[CH:19]=3)[C:9]2=[CH:10][N:11]=1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 2723923Ammonium formateHCID 68428565HCID 68428565, compound

Product 1

HCID 68427603HCID 68427603, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Prepared in analogy to that of Example 6(a) from 2,3-dibromo-1-(3-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, ammonium formate and Pd/C. The title compound, ESI MS (m/z): 327 (M+H)+.

Sources & evidence

ORD record
ord-c11c29b96b6049e3ad30b47d8d39a3d4
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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