HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)naphthalene → 3-(2-Carboxy-ethyl)-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)naphthalene | HCID 137844 | — |
| Reactant | Ethyl 3-(3-ethoxy-3-oxopropyl)-1H-indole-2-carboxylate | HCID 612032 | — |
| Product | 3-(2-Carboxy-ethyl)-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid | HCID 58900243 | — |
Reaction Steps
Using general procedure B, 3-(2-ethoxycarbonyl-ethyl)-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 372.4 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696240B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-e15ffab94e4d4a77bfe2a8cb861628df |
| Source note | uspto-grants-2010_04 |