HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)naphthalene → 1-Naphthalen-1-ylmethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)naphthalene | HCID 137844 | — |
| Reactant | Ethyl 1H-pyrrolo(2,3-b)pyridine-2-carboxylate | HCID 21868741 | — |
| Product | 1-Naphthalen-1-ylmethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid | HCID 44608259 | — |
Reaction Steps
Using general procedure B, 1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester (Adams, David Reginald et al., PCT Int. Appl. (2000), WO2000044753) was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 301.3 ([M−H]−)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696240B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-73bb9bac3fe94045b18c348f2278cb35 |
| Source note | uspto-grants-2010_04 |