Hydrochloric Acid → HCID 86615512, compound

HRID 642916Notes

Reaction equation

HRID 642916 reaction equation
C[N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][C:11]2[CH:20]=[C:19]3[C:14]([CH:15]=[CH:16][C:17](=[O:21])[O:18]3)=[CH:13][CH:12]=2)[CH2:4][C:3]1([CH3:23])[CH3:22].CCOC(/N=N/C(OCC)=O)=O.[ClH:36]>C1(C)C=CC=CC=1>[ClH:36].[CH3:8][C:7]1([CH3:9])[CH2:6][CH:5]([O:10][C:11]2[CH:20]=[C:19]3[C:14]([CH:15]=[CH:16][C:17](=[O:21])[O:18]3)=[CH:13][CH:12]=2)[CH2:4][C:3]([CH3:23])([CH3:22])[NH:2]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 5462977Diethyl azodicarboxylateHCID 11709455HCID 11709455, compound

Product 1

HCID 86615512HCID 86615512, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
115 °C

Procedure

A mixture of 7-(1,2,2,6,6-pentamethyl-piperidin-4-yloxy)-chromen-2-one (0.69 g, 2.2 mmol), diethylazodicarboxylate (1.0 ml, 6.6 ml) and toluene (50 ml) was stirred at 115° C. for 15 h. Hydrochloric acid (10 ml, 2 N) was added to the mixture and was refluxed for 1 h. The mixture was cooled and the product precipitated as the hydrochloric acid salt. Yield 0.26 g (37%). Mp>300° C.

Workup

  1. temperaturewas refluxed for 1 h
  2. temperatureThe mixture was cooled
  3. customthe product precipitated as the hydrochloric acid salt

Sources & evidence

ORD record
ord-610de2995ea84d378db65cb2f0fedd6a
Source dataset
uspto-grants-2010_04
Patent number
US07696350B2

Reaction notes

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