Water → HCID 9904297, compound

HRID 643059Notes

Reaction equation

HRID 643059 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=1.[C:15]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])(=[O:18])[NH:16][NH2:17].O>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:14]=[CH:13][C:10](/[CH:11]=[N:17]/[NH:16][C:15]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])=[CH:9][CH:8]=1

Participants

5

Reactant 3

HCID 962WaterHCID 70091tert-Butyl carbazateHCID 15152404-Pyridin-2-ylbenzaldehyde

Product 1

HCID 9904297HCID 9904297, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-(2-Pyridyl)benzaldehyde (15 g, 0.082 mol) was dissolved in ethanol (150 mL) and treated with t-butyl carbazate (10.3 g, 0.078 mol) at 80° C. for 4 h. The mixture was combined with water (200 mL), the solids were filtered, washed with water, and dried under vacuum to give 22.5 g (92%) of the title compound.

Workup

  1. filtrationthe solids were filtered
  2. washwashed with water
  3. customdried under vacuum

Sources & evidence

ORD record
ord-c063e217641d4e599c9e4d0a06069fe6
Source dataset
uspto-grants-2010_04
Patent number
US07696226B2

Reaction notes

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