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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 643333Generated: October 28, 2026

2-Chloro-3-(trifluoromethyl)benzyl alcohol → 3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}phenyl)cinnoline

https://huagongshe.com/reaction/643333

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-3-(trifluoromethyl)benzyl alcoholHCID 2778108—
Reactant3-(8-Chloro-3-phenylcinnolin-4-yl)phenolHCID 11856439—
Product3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}phenyl)cinnolineHCID 11854570—

Reaction Steps

The title compound was prepared from 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenol and (2-chloro-3-trifluoromethyl-phenyl)-methanol according the procedure of Example 55. MS (ES) m/z 538.7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700595B2
Source datasetuspto-grants-2010_04
ORD IDord-fdd125169da84219aab81fefb14c11c6
Source noteuspto-grants-2010_04