HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68579161, compound → Cysteine Protease inhibitor
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68579161 | HCID 68579161 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | Cysteine Protease inhibitor | HCID 12000657 | — |
Reaction Steps
A solution of [3′-(2-cyano-pyrimidin-4-yloxy)-biphenyl-4-ylmethyl]-carbamic acid tert-butyl ester (10 mg) in formic acid (0.154 ml) is stirred at rt for 1 h. This solution is evaporated under reduced pressure. The remaining oil is treated with diethyl ether to obtain crystals of 4-(4′-aminomethyl-biphenyl-3-yloxy)-pyrimidine-2-carbonitrile as salt with formic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700605B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-c73d254753694664a3b2da5a0731dd8b |
| Source note | uspto-grants-2010_04 |