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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 643497Generated: October 29, 2026

HCID 68579161, compound → Cysteine Protease inhibitor

https://huagongshe.com/reaction/643497

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68579161HCID 68579161—
SolventFormic AcidHCID 284—
ProductCysteine Protease inhibitorHCID 12000657—

Reaction Steps

A solution of [3′-(2-cyano-pyrimidin-4-yloxy)-biphenyl-4-ylmethyl]-carbamic acid tert-butyl ester (10 mg) in formic acid (0.154 ml) is stirred at rt for 1 h. This solution is evaporated under reduced pressure. The remaining oil is treated with diethyl ether to obtain crystals of 4-(4′-aminomethyl-biphenyl-3-yloxy)-pyrimidine-2-carbonitrile as salt with formic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700605B2
Source datasetuspto-grants-2010_04
ORD IDord-c73d254753694664a3b2da5a0731dd8b
Source noteuspto-grants-2010_04