HRID643576

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ccc(C)n1C1C=C[C@@](C(=O)NCc2cc(C(F)(F)F)ccc2OC(C)(C)C)(C(C)C)C1

HCID58617139

未命名化合物

结构：COC(=O)c1cccc(C2CCN(C3CC[C@@](C(=O)OCc4ccccc4)(C(C)C)C3)CC2)c1

HCID58617156

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1cccc(C2CCN(C3CC[C@@](C(=O)O)(C(C)C)C3)CC2)c1

HCID58617140

未命名化合物

PROCEDURE

实验过程

(1S)-1-Isopropyl-3-{4-[3-(methoxycarbonyl)phenyl]piperidin-1-yl}cyclopentane carboxylic acid was synthesized as described for INTERMEDIATE 3 (procedure A, step F) using methyl 3-(1-{(3S)-3-[(benzyloxy)carbonyl]-3-isopropylcyclopentyl}piperidin-4-yl)benzoate as starting material. The desired was obtained as a 10:1 mixture of cis: trans around the cyclopentane ring.

WORKUP

后处理

customThe desired was obtained as a 10:1 mixture of cis