HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 3,4,4-Trimethoxypiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 1-Boc-3,4,4-trimethoxypiperidine | HCID 59263089 | — |
| Product | 3,4,4-Trimethoxypiperidine | HCID 19883516 | — |
Reaction Steps
The title compound was prepared by taking tert-butyl 3,4,4-trimethoxypiperidine-1-carboxylate (424 mg, 0.00154 mol) in Methylene chloride (10 mL, 0.2 mol) and adding Trifluoroacetic Acid (1 mL, 0.02 mol). The reaction was stirred for 3 h. The solvent was removed in vacuo and the crude taken to the next step (270 mg, 99%). MS calculated for C8H17NO3: (M+H) 176; found 176.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700624B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-cb10ae74227e4a48b1fbd9960c4da118 |
| Source note | uspto-grants-2010_04 |