HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Ethyl 3-methoxy-4-oxopiperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 3,4,4-Trimethoxypiperidine-1-carboxylate | HCID 86613286 | — |
| Product | Ethyl 3-methoxy-4-oxopiperidine-1-carboxylate | HCID 2724451 | — |
Reaction Steps
The title compound was prepared by taking 3,4,4-trimethoxypiperidine-1-carboxylate (210 mg, 0.00085 mol) in Methanol (5 mL, 0.1 mol) and adding 4 M of Hydrogen chloride in 1,4-dioxane (5 mL). The reaction was allowed to stir for 4 h at ambient temperature. The residue obtained by removing the solvent in vacuo was used in the next step as-is (170 mg, 99%). MS calculated for C9H15NO4: (M+H) 202; found 202.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700624B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-57f1dff849444a4a8bdd1ee352ccdd46 |
| Source note | uspto-grants-2010_04 |