反应详情

Thionyl chloride (200 mL, 326.2 grams, 2742 mmol) is added to the solid title A compound, 4-benzyloxybenzenesulfonic acid sodium salt, followed by 10 drops of DMF. The mixture is heated to reflux overnight and then concentrated under vacuum. Hot toluene (250 mL) is added, and the mixture is filtered. The filtrate is concentrated under vacuum. Toluene is again added to the residue followed by filtration and concentration under vacuum to give 4-benzyloxybenzenesulfonyl chloride as a white solid.

1. temperatureThe mixture is heated
2. temperatureto reflux overnight
3. concentrationconcentrated under vacuum
4. additionHot toluene (250 mL) is added
5. filtrationthe mixture is filtered
6. concentrationThe filtrate is concentrated under vacuum
7. additionToluene is again added to the residue
8. filtrationfollowed by filtration and concentration under vacuum