T-2307 free base → HCID 67370195, compound

Participants

Reaction Steps

To an ethanol (10 mL) suspension of 0.50 g of 4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}benzamidine was added 1.77 mL of a 2.6 mol/mL hydrogen chloride/ethanol solution at room temperature, which was then stirred at room temperature for 4 hours and 15 minutes. The precipitate was collected by filtration to provide 0.49 g of 4-{3-[4-(3-{4-[amino(imino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}benzamidine hydrochloride as colorless solid form.

Provenance & Evidence