HRID644233

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21906418

2-Amino-5-chloro-N-(5-chloropyridin-2-yl)benzamide

C12H9Cl2N3O

结构：CSc1ccc(C(=O)O)c(OCCNC(=O)OC(C)(C)C)c1

HCID57936572

未命名化合物

PRODUCTS

生成物

结构：CSc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(OCCNC(=O)OC(C)(C)C)c1

HCID68533941

未命名化合物

PROCEDURE

实验过程

2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]-4-(methylthio)benzoylamino]-5-chloro-N-(5-chloropyridin-2-yl)benzamide was prepared by methods described in example 4-E from 2-[2-(tert-butoxycarbonylamino)ethoxy]-4-(methylthio)benzoic acid and N-(5-chloropyridin-2-yl)-2-amino-5-chlorobenzamide (3 g, 92%). IR (CHCl3): 1665, 1500, 1375, 1296 cm−1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0a71aaa0a1404b9ba18a2aafd1b9ce7b
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07700628B2
来源说明: uspto-grants-2010_04

反应 SMILES

[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:20]=[C:19]([S:21][CH3:22])[CH:18]=[CH:17][C:13]=1[C:14]([OH:16])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl:23][C:24]1[CH:25]=[CH:26][C:27]([NH:30][C:31](=[O:40])[C:32]2[CH:37]=[C:36]([Cl:38])[CH:35]=[CH:34][C:33]=2[NH2:39])=[N:28][CH:29]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:20]=[C:19]([S:21][CH3:22])[CH:18]=[CH:17][C:13]=1[C:14]([NH:39][C:33]1[CH:34]=[CH:35][C:36]([Cl:38])=[CH:37][C:32]=1[C:31]([NH:30][C:27]1[CH:26]=[CH:25][C:24]([Cl:23])=[CH:29][N:28]=1)=[O:40])=[O:16])=[O:7])([CH3:2])([CH3:3])[CH3:4]