HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-chloroaniline → HCID 57860927, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-chloroaniline | HCID 610169 | — |
| Reactant | 6-Fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)phenyl]-4H-3,1-benzoxazin-4-one | HCID 57860842 | — |
| Reactant | HCID 86634212 | HCID 86634212 | — |
| Product | HCID 57860927 | HCID 57860927 | — |
Reaction Steps
Using methods substantially equivalent to those described in Example 118, N-(4-bromo-2-chlorophenyl)-5-fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoylamino]benzamide trifluoroacetate was prepared from 6-fluoro-2-[4-(pyrrolidin-1-yl)-2-(1-methylpiperidin-4-yloxy)phenyl]-4H-3,1-benzoxazin-4-one and 4-bromo-2-chloroaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700628B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-c96d2344671040dea97bdfaa6ca8ec9e |
| Source note | uspto-grants-2010_04 |