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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 644262Generated: October 28, 2026

2-Chloro-4-nitroaniline → HCID 57860813, compound

https://huagongshe.com/reaction/644262

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-nitroanilineHCID 8492—
Reactant6-Fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)phenyl]-4H-3,1-benzoxazin-4-oneHCID 57860842—
ReactantHCID 68534983HCID 68534983—
ProductHCID 57860813HCID 57860813—

Reaction Steps

Using methods substantially equivalent to those described in Example 118, N-(2-chloro-4-nitrophenyl)-5-fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoylamino]benzamide trifluoroacetate was prepared from 6-fluoro-2-[4-(pyrrolidin-1-yl)-2-(1-methylpiperidin-4-yloxy)phenyl]-4H-3,1-benzoxazin-4-one and 2-chloro-4-nitroaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700628B2
Source datasetuspto-grants-2010_04
ORD IDord-6c1e7b113bd047c2b4cc4238ba31405d
Source noteuspto-grants-2010_04