HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl (R)-2-acetylamino-3-(3,4-diethyl-phenyl)-propionate → (2R)-2-Amino-3-(3,4-diethylphenyl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl (R)-2-acetylamino-3-(3,4-diethyl-phenyl)-propionate | HCID 69711472 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | (2R)-2-Amino-3-(3,4-diethylphenyl)propanoic acid | HCID 45095428 | — |
Reaction Steps
A mixture of 13.8 g (47.4 mmol) ethyl (R)-2-acetylamino-3-(3,4-diethyl-phenyl)-propionate and 160 mL 6 M HCl was refluxed in the oil bath for 3 h. The reaction mixture was cooled in the ice bath and the precipitate formed was suction filtered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700589B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-5a42f67f08a7462f892b1654d621e1b6 |
| Source note | uspto-grants-2010_04 |