HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-difluoro-1,4'-bipiperidine → HCID 10417127, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-difluoro-1,4'-bipiperidine | HCID 53418774 | — |
| Reactant | (R)-3-(3,4-diethyl-phenyl)-2-{[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyl]-amino}-propionic acid | HCID 68579001 | — |
| Product | HCID 10417127 | HCID 10417127 | — |
Reaction Steps
Prepared analogously to Example 9i) from 400 mg (0.81 mmol) (R)-3-(3,4-diethyl-phenyl)-2-{[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyl]-amino}-propionic acid and 200 mg (0.98 mmol) 4,4-difluoro-[1,4′]bipiperidinyl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700589B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-934ce007f9fa429c8046a0e448cd83b3 |
| Source note | uspto-grants-2010_04 |