HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23153399, compound → 4-(Azetidin-1-YL)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23153399 | HCID 23153399 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(Azetidin-1-YL)piperidine | HCID 23153109 | — |
Reaction Steps
3.2 g (13.9 mmol) 4-azetidin-1-yl-1-benzyl-piperidine dissolved in 50 mL MeOH were hydrogenated in the autoclave in the presence of 0.5 g Pd/C (10%) at 50° C. and 3 bar hydrogen pressure until the calculated volume of hydrogen had been taken up. The catalyst was filtered off and the solvent was eliminated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700589B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-a920274d7d824753a91b7afa7bd1fc4f |
| Source note | uspto-grants-2010_04 |