HRID644369

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7183041

1-methyl-4,4'-bipiperidine

C11H22N2

结构：Cc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)O)cc1C

HCID68581057

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(C)CC3)CC2)cc1C

HCID59260966

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 76e) from 2-(3,4-dimethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butanoic acid and 1-methyl-[4,4′]bipiperidinyl

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8916242f314f41488921c7f46a152fbf
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07700589B2
来源说明: uspto-grants-2010_04

反应 SMILES

[CH3:1][C:2]1[CH:3]=[C:4]([CH:30]=[CH:31][C:32]=1[CH3:33])[CH2:5][CH:6]([CH2:10][C:11](=[O:29])[N:12]1[CH2:17][CH2:16][CH:15]([N:18]2[CH2:27][C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[NH:20][C:19]2=[O:28])[CH2:14][CH2:13]1)[C:7]([OH:9])=O.[CH3:34][N:35]1[CH2:40][CH2:39][CH:38]([CH:41]2[CH2:46][CH2:45][NH:44][CH2:43][CH2:42]2)[CH2:37][CH2:36]1>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:30]=[CH:31][C:32]=1[CH3:33])[CH2:5][CH:6]([CH2:10][C:11]([N:12]1[CH2:13][CH2:14][CH:15]([N:18]2[CH2:27][C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[NH:20][C:19]2=[O:28])[CH2:16][CH2:17]1)=[O:29])[C:7]([N:44]1[CH2:45][CH2:46][CH:41]([CH:38]2[CH2:37][CH2:36][N:35]([CH3:34])[CH2:40][CH2:39]2)[CH2:42][CH2:43]1)=[O:9]