1-Methyl-4,4'-bipiperidine → 2-(3,4-dimethyl-benzyl)-1-(1'-methyl-[4,4']bipiperidinyl-1-yl)-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butan-1,4-dione

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-4,4'-bipiperidine	HCID 7183041	—
Reactant	2-(3,4-dimethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butanoic acid	HCID 68581057	—
Product	2-(3,4-dimethyl-benzyl)-1-(1'-methyl-[4,4']bipiperidinyl-1-yl)-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butan-1,4-dione	HCID 59260966	—

Reaction Steps

Prepared analogously to Example 76e) from 2-(3,4-dimethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butanoic acid and 1-methyl-[4,4′]bipiperidinyl

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07700589B2
Source dataset	uspto-grants-2010_04
ORD ID	ord-8916242f314f41488921c7f46a152fbf
Source note	uspto-grants-2010_04