HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 2-amino-4-(tert-butyl)-1,3-thiazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | Bromo-pivaloylacetonitrile | HCID 11586483 | — |
| Product | 2-amino-4-(tert-butyl)-1,3-thiazole-5-carbonitrile | HCID 2768518 | 66.3% |
Reaction Steps
Using α-bromo-pivaloylacetonitrile and thiourea as the raw materials, the same operation as the Example 181(1) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700655B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-4c6199ff78b24ddc8b4a140d16772ad2 |
| Source note | uspto-grants-2010_04 |