HRID644478

反应详情

EQUATION

反应方程式

HRID 644478 的结构方程式

REACTANTS

反应物

2

结构：CC(=O)c1ccc(C(F)(F)F)cc1

1-(4-(Trifluoromethyl)phenyl)ethan-1-one

C9H7F3O

结构：NC(N)=S

Thiourea

CH4N2S

PRODUCTS

生成物

1

结构：Nc1nc(-c2ccc(C(F)(F)F)cc2)cs1

4-[4-(Trifluoromethyl)phenyl]-1,3-thiazol-2-amine

C10H7F3N2S

收率 77.5%

PROCEDURE

实验过程

Using 4′-(trifluoromethyl)acetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.