HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-(Trifluoromethyl)phenyl)ethan-1-one → 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-(Trifluoromethyl)phenyl)ethan-1-one | HCID 69731 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Product | 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine | HCID 2737741 | 77.5% |
Reaction Steps
Using 4′-(trifluoromethyl)acetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700655B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-3f0e646ad3894f0e8ba95cded9d4b5ee |
| Source note | uspto-grants-2010_04 |