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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 644495Generated: October 30, 2026

3'-(Trifluoromethyl)acetophenone → 4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine

https://huagongshe.com/reaction/644495

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3'-(Trifluoromethyl)acetophenoneHCID 67682—
ReactantThioureaHCID 2723790—
Product4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amineHCID 70645794.1%

Reaction Steps

Using 3′-(trifluoromethyl)acetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700655B2
Source datasetuspto-grants-2010_04
ORD IDord-67f4dfcfbc8a405ea17ff3319acd241c
Source noteuspto-grants-2010_04