HCID 68717789, compound → HCID 68716121, compound

Participants

Reaction Steps

0.72 g of the N-(6-acryloylaminocaproyl)phenylalanine ethyl ester obtained in Reference Example 13 was added to 50 ml of methanol containing 1 N sodium hydroxide, followed by stirring at room temperature for 4 hours. After the reaction, an H+ cation exchange resin, Dowex 50W (Dow Chemical Co.), was added for neutralization. The ion exchange resin was then filtered off, and the filtrate was evaporated to afford the target compound (0.65 g).

Provenance & Evidence