HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,8-dimethyl-4-oxo-4H-[1,7]naphthyridine-1,3-dicarboxylic acid 1-benzyl ester 3-ethyl ester → HCID 58662434, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,8-dimethyl-4-oxo-4H-[1,7]naphthyridine-1,3-dicarboxylic acid 1-benzyl ester 3-ethyl ester | HCID 58662448 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Catalyst | Copper iodide | HCID 83717 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58662434 | HCID 58662434 | — |
Reaction Steps
This compound can be obtained by reacting a stirred suspension of 6,8-dimethyl-4-oxo-4H-[1,7]naphthyridine-1,3-dicarboxylic acid 1-benzyl ester 3-ethyl ester, prepared in step (iii) and CuI (copper iodide) in THF, with freshly prepared EtMgBr (ethyl magnesium bromide) at −78° C., followed by a typical workup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700774B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-372cfc7d633b46938fe3c2f4841a3745 |
| Source note | uspto-grants-2010_04 |